Recent Advances in the Pathogenesis, Prevention and Management of Type 2 Diabetes and its Complications

Recent Advances in the Pathogenesis, Prevention and Management of Type 2 Diabetes and its Complications

Author: Mark Zimering

Publisher: IntechOpen

ISBN: 953307597X

Category: Medical

Page: 456

View: 655

Type 2 diabetes "mellitus" affects nearly 120 million persons worldwide- and according to the World Health Organization this number is expected to double by the year 2030. Owing to a rapidly increasing disease prevalence, the medical, social and economic burdens associated with the microvascular and macrovascular complications of type 2 diabetes are likely to increase dramatically in the coming decades. In this volume, leading contributors to the field review the pathogenesis, treatment and management of type 2 diabetes and its complications. They provide invaluable insight and share their discoveries about potentially important new techniques for the diagnosis, treatment and prevention of diabetic complications.

Recent Advances in the Pathogenesis, Prevention and Management of Type 2 Diabetes and its Complications

Recent Advances in the Pathogenesis, Prevention and Management of Type 2 Diabetes and its Complications

Author: Mark Zimering

Publisher: BoD – Books on Demand

ISBN: 9789533075976

Category: Medical

Page: 456

View: 280

Type 2 diabetes "mellitus" affects nearly 120 million persons worldwide- and according to the World Health Organization this number is expected to double by the year 2030. Owing to a rapidly increasing disease prevalence, the medical, social and economic burdens associated with the microvascular and macrovascular complications of type 2 diabetes are likely to increase dramatically in the coming decades. In this volume, leading contributors to the field review the pathogenesis, treatment and management of type 2 diabetes and its complications. They provide invaluable insight and share their discoveries about potentially important new techniques for the diagnosis, treatment and prevention of diabetic complications.

The 15th International Conference on Biomedical Engineering

The 15th International Conference on Biomedical Engineering

Author: James Goh

Publisher: Springer Science & Business Media

ISBN: 9783319029139

Category: Technology & Engineering

Page: 968

View: 674

This volume presents the processing of the 15th ICMBE held from 4th to 7th December 2013, Singapore. Biomedical engineering is applied in most aspects of our healthcare ecosystem. From electronic health records to diagnostic tools to therapeutic, rehabilitative and regenerative treatments, the work of biomedical engineers is evident. Biomedical engineers work at the intersection of engineering, life sciences and healthcare. The engineers would use principles from applied science including mechanical, electrical, chemical and computer engineering together with physical sciences including physics, chemistry and mathematics to apply them to biology and medicine. Applying such concepts to the human body is very much the same concepts that go into building and programming a machine. The goal is to better understand, replace or fix a target system to ultimately improve the quality of healthcare. With this understanding, the conference proceedings offer a single platform for individuals and organizations working in the biomedical engineering related field to gather and network with each other in so doing create the catalyst for future development of biomedical engineering in Asia.

Atlas of Diabetes

Atlas of Diabetes

Author: Jay Skyler

Publisher: Springer Science & Business Media

ISBN: 9781461410287

Category: Medical

Page: 422

View: 551

This handbook is an invaluable resource for improving the management of diabetes. Chapters cover the fundamentals, including epidemiology, history and physical examination, and functional evaluations. Diabetes in children, adolescents, adults, and geriatrics are addressed. Differential diagnosis is emphasized, and evidence-based guidelines and patient-specific considerations aid the reader with injury evaluation and care. Notably, the book highlights the importance of understanding diabetic symptoms when determining the source of illnesses. In addition, the text presents the spectrum of treatment options for diabetes. The book is complete with appendices that explain the evidence-based approach used throughout and the science behind therapeutic modalities.

Endocrinology Adult and Pediatric: Diabetes Mellitus and Obesity E-Book

Endocrinology Adult and Pediatric: Diabetes Mellitus and Obesity E-Book

Author: Gordon C Weir

Publisher: Elsevier Health Sciences

ISBN: 9780323221542

Category: Medical

Page: 496

View: 211

Meet the growing challenges of diabetes and obesity management with Endocrinology: Adult and Pediatric: Diabetes Mellitus and Obesity - a new diabetes and obesity eBook from the same expert endocrinologists responsible for the highly acclaimed two-volume Endocrinology clinical reference. With all of the latest advances loaded on your favorite eReader, you’ll be able to put today’s best practices to work for your patients. Stay abreast of the newest knowledge and advances in diabetes mellitus and obesity, including today’s increased focus on controlling autoimmunity and preserving or replenishing beta-cell mass in the management of type 1 diabetes; complications of diabetes and their pathogenesis, morbidity, and treatment; new findings and treatments for obesity; and much more. Count on all the authority that has made Endocrinology, 6th Edition, edited by Drs. Jameson and DeGroot, the go-to clinical reference for endocrinologists worldwide. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices.

Therapy for Diabetes Mellitus and Related Disorders

Therapy for Diabetes Mellitus and Related Disorders

Author: Guillermo Umpierrez

Publisher: American Diabetes Association

ISBN: 9781580405096

Category: Medical

Page: 704

View: 218

Nearly 100 of the world's leading medical researchers and clinicians share their expertise on the diagnosis, treatment, and care of people with diabetes mellitus. This newly revised sixth edition is a comprehensive guide to type 1, type 2, and gestational diabetes. New diabetes treatment strategies include medical nutrition therapy with diabetes diet and exercise programs. This guide covers the latest research on diabetes medication and technology with insulin-pump therapy, insulin secretagogues, incretin mimetics, and medications for obesity, as well as advances in diabetes prevention. Family care topics include diabetes in pregnancy, diabetic ketoacidosis, childhood obesity, and type 2 diabetes in children. Other topics include glycemic control, diabetes complications and comorbidities, diabetes mellitus therapy in different patient groups, and much more. This is an excellent resource for physicians seeking to provide the most current treatment for their patients. Therapy for Diabetes Mellitus and Related Disorders is the most comprehensive clinical reference work available on the disease.

Endocrine System Diseases—Advances in Research and Treatment: 2012 Edition

Endocrine System Diseases—Advances in Research and Treatment: 2012 Edition

Author:

Publisher: ScholarlyEditions

ISBN: 9781464993541

Category: Medical

Page: 437

View: 962

Endocrine System Diseases—Advances in Research and Treatment: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Endocrine System Diseases. The editors have built Endocrine System Diseases—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Endocrine System Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Endocrine System Diseases—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Research on Diabetes I

Research on Diabetes I

Author: Iconcept Press

Publisher: CreateSpace

ISBN: 1477555013

Category: Medical

Page: 314

View: 876

Chapter 1 provides a brief overview of mechanisms underlying glucose-stimulated insulin secretion by pancreatic beta cells highlighting the role of mitochondria. It presents a novel way to further explore possible involvement of mitochondrial dysfunction in beta cell glucolipotoxicity. Chapter 2 discusses acute pancreatitis, which has often a biliary pathogenesis. The in-depth knowledge of the relationship between these diabetes and acute pancreatitis can encourage an effective prevention and also a better therapeutics stage management. Chapter 3 addresses the key points of occurrence, pathophysiology of type-II diabetes in morbid obesity and treatment options focusing mainly on bariatric surgery and its mechanism of action and outcomes in obese diabetic individuals. Chapter 4 discusses the possible causes that produce podocytopenia and how the loss of podocytes can alter the glomerular filtration barrier structural organization and consequently, contribute toproteinuria in DN. Chapter 5 focuses on the physiologic roles of leptin and ghrelin in energy homeostasis and how H. pylori colonization as well as eradication affects these functions in the context of metabolic regulation. Chapter 6 discusses connexin and pannexin proteins. Membrane channels formed by connexin (gap junction intercellular channels and hemichannels) and pannexin proteins play a central role in the control and coordination of vasomotor tone in the microcirculation. Connexin- and/or pannexin-mediated signaling in the vessel wall is altered or reduced in diabetes, which contributes to the vascular dysfunction typically observed during the development of this disease. In Chapter 7, protein energy profiling is used as a methodology to analyze and discuss energeticdiscrepancies and destabilizations observed in structure models of membrane proteins involved innephrogenic diabetes insipidus. Chapter 8 describes the development and utilization of an adult model of type I diabetes mellitus. This model is unique in that it allows for efficient dissection of the molecular pathways underlying the persistence of diabetic complications. Chapter 9 discusses issues related to medical management of pregnant women with inflammatory bowel disease. Therapeutic options for inflammatory bowel disease during pregnancy are limited due to the concerns for the safety of fetus, despite great advances in medical treatments. Chapter 10 describes the complicated skin and skin-structure infections (emphasizing footinfections) found in diabetics, and the bacteria that are most commonly isolated from these infections. Chapter 11 describes the main animal models used in diabetes research studies and their most important metabolic characteristics, pathology andmethods of induction. Their differences and similarities to the human condition are presented in the aim to assist researchers in selecting the most appropriate model for their study. Chapter 12 summarizes current knowledge on genetic and nutritional animal models to study NASH. As many animal models of NASH have been developed to date, advantages and disadvantages are described. Chapter 13 discusses how hydrogen-rich water can inhibit the production of certain compounds in the kidney and the prevention of the development of renal damage in SHR.Cg-Leprcp/NDmcr rat, a model of metabolic syndrome. Chapter 14 summarizes overall technologies for {\itshape in vivo} imaging of mouse pancreas, and focused on bioluminescence imaging of the pancreas using transgenic mice carrying luciferase gene drived by the promoter of insulin or bone morphogenetic protein genes. Chapter 15 provides data supporting the importance of autophagy lysosomal pathway in triacylglycerol degradation in the liver.

Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome

Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome

Author: Debasis Bagchi

Publisher: Academic Press

ISBN: 9780128120088

Category: Medical

Page: 554

View: 179

Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome, Second Edition, provides an overview of the current diabetes epidemic, outlines the consequences of this crisis, and lays out strategies to forestall and prevent diabetes, obesity and other intricate issues of metabolic syndrome. Contributing experts provide up-to-date global approaches to the critical consequences of metabolic syndrome and make the book an important reference for those working with the treatment, evaluation or public health planning for the effects of metabolic syndrome and diabetes. Completely revised with 15 new chapters, the book includes coverage of the roles of gut microbiome in obesity and diabetes, macrovascular and microvascular complications, diabetes, metabolic syndrome and kidney disease, aspects of diabetic cardiomyopathy, diabetes, Alzheimer’s and neurodegenerative diseases, roles of SGLT2 inhibitors in the treatment of type 2 diabetes, novel biomarkers in diabetes, roles of Trigonella foenum-graecumseed extract in type 2 diabetes, beneficial effects of chromium (III) and vanadium supplements in diabetes, prevention of type 1 diabetes, novel drugs in the therapeutic intervention of type 2 diabetes, eHealth and mobile apps for self-management, artificial pancreatic transplantation, non-invasive glucose monitoring, and the app for glucose regulation. Contains a scientific discussion of the epidemiology and pathophysiology of the relationship between diabetes and metabolic syndrome Includes coverage of Pre-diabetes conditions, plus both Type I and Type II Diabetes Presents both prevention and treatment options

Oxford Textbook of Medicine

Oxford Textbook of Medicine

Author: David A. Warrell

Publisher: Oxford University Press, USA

ISBN: 9780192629227

Category: Medical

Page: 4500

View: 388

The Oxford Textbook of Medicine provides all that any doctor needs to know to practice top-level internal medicine. It gives compreensive coverage of the epidemiology, aetiology, and mechanism of disease, as well as clear, unambiguous coverage of the diagnosis, practical management and prevention of the entire spectrum of medical disorders. There are major introductory sections on the scientific basis of disease; and in the system-based clinical sections genetic predisposition, pathophysiology, pathogenesis, molecular mechanisms, and cell biology are covered in depth for all significant medical syndromes. Clinical descriptions of diseases are clearly and memorably written, based on the experience and insight of the authors--many of whom are among the world's most distinguished medical scientists. Chapters are not only "evidence based" but also on clinical experience and a thorough survey of all the relevant literature. Throughout, the approach of OTM is humane and ethical and, at the same time, factual, reliable, honest(especially where knowledge is limited) and rigorously scientific. This is not just a textbook of "First World" medicine. It provides practical guidance for doctors working in a variety of medical setting the value of a logical clinical approach rather than immediate resort to expensive imaging and laboratory tests. Moore of the contributing authors than ever before are from outside Europe, including strong representation of North American medicine. The new editorial team has ensured that the OTM continues to reflect rapid changes in medical practice: there are new sections on intensive care, alcohol and drug abuse, clinical pharmacology and therapeutics, world health, clinical trials and evidence-based medicine, adolescent medicine, sports medicine, and emergency medicine; more than half the contributors are new for this edition; and most of the text has been heavily revised. The striking new page and cover design reflect the significant changes made in this new edition. The Textbook is illustrated by over 2000 two-color diagrams and many color Plates. The index is the most detailed and user-friendly of any major medical textbook: in an emergency, the reader can access information quickly- whether on the ward, in office or at home. Like its predecessors, OTM4 will be the trusted and ultimate reference in libraries, hospitals, doctors' consulting rooms, solicitors' offices, press offices, and primary care practices worldwide.

The Diabetic Kidney

The Diabetic Kidney

Author: Pedro Cortes

Publisher: Springer Science & Business Media

ISBN: 9781597451536

Category: Medical

Page: 564

View: 520

A comprehensive and authoritative survey of recent findings, ideas, and hypotheses about the causes and treatment of diabetic nephropathy. The authors cover both the basic pathogenic mechanisms of the disease, as well as many of its clinical aspects of identification, management, and new therapeutic approaches. Highlights include an entire section devoted to novel approaches to studying diabetic nephropathy with the most advanced molecular techniques, and complete descriptions of the most up-to-date views on the diagnosis and treatment of the disease. The Diabetic Kidney offers both researchers and practicing clinicians a clear understanding of the of the progress that has been made regarding the pathogenesis of diabetic nephropathy and of the therapeutic interventions needed to prevent its development or treat it.