The branch of biology that deals with the study of the molecular basis of biological activity between biomolecules in different systems of a cell is referred to as molecular biology. It includes the interactions between DNA, RNA, proteins and their biosynthesis along with the regulation of these interactions. Molecular biology also makes use of techniques and concepts from the fields of genetics and biochemistry. Some of the techniques used within this field are molecular cloning, polymerase chain reaction, gel electrophoresis and allele-specific oligonucleotide. There are numerous processes which are studied within molecular biology such as replication, transcription and cell function. This book is a compilation of chapters that discuss the most vital concepts in the field of molecular biology. While understanding the long-term perspectives of the topics, it makes an effort in highlighting their impact as a modern tool for the growth of the discipline. This textbook will provide comprehensive knowledge to the readers.
Principles of Cell Biology, Third Edition is an educational, eye-opening text with an emphasis on how evolution shapes organisms on the cellular level. Students will learn the material through 14 comprehensible principles, which give context to the underlying theme that make the details fit together.
As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.
The concept of molecular medicine dates back to Linus means that there are many new opportunities and challenges Pauling, who in the late 1940s and early 1950s generalized for clinical medicine. One of the effects of the completion of from the ideas that came from the study of the sickle cell the Human Genome Project is the increasing application of hemoglobin molecule. With the first cloning of human genes the fields of molecular biology and genetics to the und- about 1976, molecular genetics took the molecular perspec- standing and management of common diseases. Assimi- tive on disease to the level of DNA. The term molecular tion of the new developments since the first edition has been medicine achieved wide currency in the 1980s with the ably accomplished by Drs. Runge and Patterson with the assignment of this designation to journals, at least one soci- help of their many knowledgeable authors. ety, institutes, and academic divisions of departments of in- As was evident in the first edition, molecular genetics is ternal medicine. Undoubtedly, molecular medicine has been involved in every specialty of medicine. A recurrent theme abetted by the Human Genome Project, which has aided in that edition, perhaps even more striking in the present one, greatly in the molecular characterization of disease.
Bioinformatics, which can be defined as the application of computer science and information technology to the field of biology and medicine, has been rapidly developing over the past few decades. It generates new knowledge as well as the computational tools to create that knowledge. Understanding the basic processes in living organisms is therefore indispensable for bioinformaticians. This book addresses beginners in molecular biology, especially computer scientists who would like to work as bioinformaticians. It presents basic processes in living organisms in a condensed manner. Additionally, principles of several high-throughput technologies in molecular biology, which need the assistance of bioinformaticians, are explained from a biological point of view. It is structured in the following 9 chapters: cells and viruses; protein structure and function; nucleic acids; DNA replication, mutations, and repair; transcription and posttranscriptional processes; synthesis and posttranslational modifications of proteins; cell division; cell signaling pathways; and high-throughput technologies in molecular biology.
This book provides a detailed and thorough review of the Cell and Molecular Biology topics tested on the 2019 GRE Biology exam. The content covers foundational principles and theories necessary to answer related questions on the test. The information is presented clearly and organized systematically to provide students with targeted review tool.
: Designed to fill the existing gap between simple introductory texts and very advanced reviews of major virus families, Principles of Virology introduces upper–level undergraduates, graduate students, and medical students to all aspects of virology. Written in an engagingly readable style and generously illustrated with over 400 full–color illustrations, this approachable volume offers detailed examples that illustrate common principles, specific strategies adopted by different viruses to ensure their reproduction, and the current state of virology research. Divided into chapters focusing on specific topics rather than individual viruses, the book allows the student to visualize common themes in replication that cut across virus families, emphasizing the shared features of different viruses. Drawing on the extensive teaching experience of each of its distinguished authors, Principles of Virology illustrates why and how animal viruses are studied, taking well–known systems and demonstrating how the knowledge gained from these model viruses can be used to study viral systems about which our knowledge is still quite limited. A discussion of viruses in early human cultures, how viruses were discovered, and how the discipline of virology came to be is also provided.